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XUE Xiaoyan, JANG Hua, LIU Congmin

( Department of Jiaozuo Special lnspection, No.988 Hospital of Joint Logistic Support Force, Jiaozuo 454000, China)

Abstract Objective :To explore the correlation between echocardiography, serum homocysteine( Hcy) levels and CT pulmonary embolism obstruction index( PAOI) in patients with acute pulmonary embolism( APE), as well as itsvalue in predicting therapeutic efficacy. Methods 149 patients with APE were selected for the study, and wereclassified as mild( PAOI score<30%)45 cases, moderate(30%<PAOI score<50%)58 cases, and severe( PAOI score >50% )46 cases, and the correlation of cardiovascular parameters, serum Hcy level and PAOI at admissionand their predictive value of the therapeutic eicacy were analyzed. Results At admission, the right atrial end-systolic diameter ( RAESD ) , right ventricular end-diastolic diameter (RVEDD), main pulmonary artery diameter( MPA ) , systolic pulmonary artery pressure( SPAP) , and Hcy levels were higher in severe patients than in moderatepatients and mild patients, and the difference was statistieally significant (P<0.05). At admission, RAESD,RVEDD, MPA, SPAP, and serum Hey levels were positively correlated with PAOI( P<0.05). Compared witheffective patients, the RAESD, RVEDD, MPA, SPAP , and Hey levels were higher in inelfective patients after 1, 2, and 3 weeks of treatment( P<0.05). The ROC curve showed that the AUC of RAESD, RVEDD, MPA, SPAP, andHey combined to predict inelflective treatment of APE after 1, 2 and 3 weeks of treatment were 0.877,0.922 and 0.934, respectively ( P<0.05). Conclusion Echocardiography parameters and Hey reflect the condition of patientswith APE, and when combined, they can predict the risk of inellective APE treatment, providing guidanee forimproving treatment plans.

Keywords: acute pulmonary embolism; echocardiography; serum homocysteine; pulmonary embolism obstruction index

DOI:10.19296/i.cnki.1008-2409.2024-04-010

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