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REN Qi ¢Ú , LIU Lu, CHEN Wanyi

(Dept. of Neurology, the Fourth Affiliated Hospital of Guangzhou Medical University,Guangzhou 511300, China)

Abstract Objective: To investigate the status and risk factors of cognitive function recovery in patients with cevebral ischemic stroke (CIS) after thrombolytic therapy. Methods: A total of 80 CIS patients were selected, whose cognitive function recovery and the risk factors for abnormal cognitive function recovery of CIS patients after thrombolytic therapy were statistically analyzed. Results: Among 80 patients,11 patients (accounting for 13. 75 % ) had suffered from abnormal cognitive function recovery. Logistic regression analysis showed that older age, higher NIHSS score, time from onset to thrombolysis ¡Ý4.5 h and metabolic syndrome were risk factors for abnormal cognitive function recovery in CIS patients after thrombolytic therapy (OR>1, P<0.05). Conclusion: The abnormal recovery of cognitive function in CIS patients after thrombolytic therapy is related to older age, higher NIHSS score, time from onset to thrombolysis ¡Ý4.5 h, metabolic syndrome, and the like.

Keywords: cevebral ischemic stroke; thrombolysis; cognitive function; neurological deficits; metabolic syndrome

DOI:10.19296/ j.cnki.1008-2409.2023-01-021

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