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ZHANG Hanghang^a,FENG Weihua^b,lE Ruofei^a,ANG Xue^b

( a. Department of Anesthesia and Perioperative Medicine, b. Division I of Department of Bone andJoint Infection , Luoyang Orhopaedie Hospital/Zhengzhou District of Henan OrthopaedicHospital.Zhengzhou 450000.China)

0bjective To explore the application efects of vacuum sealing drainage( VSD ) based on theAbstractconcept of trauma protection in promoting wound healing and reducing the risk of wound infection inpatients with osteomyelitis and bone defect after surgery. Methods 88 patients with osteomyelitis with bonedefect were selected as the study subjects, with 44 cases in each group. The control group were receivedperioperative management according to clinical nursing path, and the study group were received the extra vacuum sealing drainage based on the concept of trauma protection. The postoperative recovery status.serum inflammatory indexes, postoperative complications and surface of a wound healing rate at stage lwere compared between the two groups. Results The times of dressing change in the study group were lessthan those in the control group, and the wound healing time, granulation tissue covering time, antibioticuse time and fracture healing time were all shorter than those in the control group, with a statisticallysignificant differenee( P<0.05 ). After intervention, the levels of lL-6, IL-8 and TNF-a in both groupswere lower than those before intervention ( P<0.05 ). The complication rate of study group was lower thanthat of control group, and the wound healing rate at stage I of study group was higher than that of controlgroup ( P<0.05 ). Conclusion Based on the concept of trauma protection, vacuum sealing drainage caneffectively promote wound healing, improve serum infammatory indexes, and reduce the risk ofcomplications.

Keywords: osteomyelitis; bone defect; surface of a wound; the concept of trauma protection; vacuumsealing drainage; inflammatory response

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