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XIE Le^1£¬2 , LlU Chuanyu³ , CHEN Shanlin¹ , SHI Guiqiao¹, QIN Kunqing¹, TANG Jianhong¹

( 1. The Second Affiliated Hospital of Guilin Medical College, Guilin 541199, China; 2. College of Pharmacy,Guilin Medical University, Guilin 541199, China; 3. Affiliated Hospital of Guilin Medical University,Guilin 541001.China)

Abstract Objective 'To observe the clinical elfect of procatterol hydrochloride granules in the treatment ofchildren with asthmatic diseases, Vethods 90 children with asthmatie diseases were included and dividedinto 3 groups according to different medication regimen, with 30 cases in each group. "The control groupwere received conventional drugs, while the procatterol group were received conventional drugs plusprocatterol hydrochloride granules, and the ambroterol group were received conventional drugs plus ambroterol oral liquid. The time of clinical symptoms improvement , the incidence of adverse reactions, andthe number of recurrent hospitalization and outpatient visits were observed in each group. Results Theimprovement time of cough , dyspnea, wheezing and pulmonary wheezing in procatrol group was shorterthan that in the ambroterol group and control group, and the differenee was statistically significant ( P<0.05 ) . There was no significant difference in the total incidence of adverse reactions among the three groups( P>0.05 ) . The incidence of 3 or more outpatient visits due to asthmatic diseases in the procaterol groupwas lower than that in the ambroterol group and control group within 1 year ( P<0. 05 ). ConclusionProcatterol hvdrochloride is more clinically effective in the treatment of children with asthmatic diseases .which can reduce the recurrence rate of the disease.

Keywor'ds : procaterol hydrochloride granules; ambroterol oral liquid; children with asthmatie diseases

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